Within the Tar Heel State, I-77 travels directly through the Queen City of Charlotte, serving Downtown in conjunction with Interstate 277, the John Belk and Brookshire Freeways. The remainder of the route in South Carolina leads north to Rock Hill and the Charlotte metropolitan area. The freeway begins at Cayce on the south side of Columbia, following the Southeastern Beltway to Fort Jackson and I-20 near Forest Acres.
Interstate 77 connects the eastern Great Lakes region with Appalachia and the Southeast.